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Todas as edições →MetodologiaAtualizado · outubro de 2026
Pesquisa de agonistas triplos de hormônios

Retatrutide.
2 fornecedors · R$417

Agonista triplo experimental dos receptores de GIP/GLP-1/glucagon (LY3437943), da Eli Lilly, estudado em ensaios de fase 3; não aprovado como medicamento em nenhum lugar e não destinado ao uso terapêutico em humanos.

Fase clínicaFrasco liofilizadoTambém conhecido como:LY3437943 · Triple Receptor Agonist · Triple G
Especificação do composto
Meia-vida
Aproximadamente 6 dias (humano; Urva et al. 2022, fase 1b)
Armazenamento
Pó liofilizado abaixo de −15 °C, bem fechado e protegido da luz; deixar o frasco selado atingir a temperatura ambiente antes de abrir. Frascos reconstituídos a 2–8 °C.
Tamanhos
5 mg, 10 mg
O que é

O composto. Origem, pesquisa e realidade regulatória.

Retatrutide (development code LY3437943) is an investigational triple hormone-receptor agonist developed by Eli Lilly: a single synthetic peptide engineered to activate the GIP, GLP-1 and glucagon receptors. As of September 2026 it has not been approved as a medicine in any jurisdiction; Lilly states it is available only to participants in its clinical trials.

A Phase 1b multiple-ascending-dose study (Urva et al., 2022) characterised its pharmacokinetics, and a Phase 2 trial (Jastreboff et al., 2023) examined its triple-receptor mechanism and dose-dependent effect on body weight in adults with obesity. The Phase 3 TRIUMPH programme is evaluating retatrutide in obesity and related conditions.

The FDA states that retatrutide cannot be used in compounding under federal law and is not a component of any FDA-approved drug, and it has warned telehealth companies, distributors and outsourcing facilities that sold unapproved retatrutide falsely labelled ‘for research purposes’ or ‘not for human consumption’. Research-use-only vials sold commercially are outside Lilly’s clinical-trial supply chain and have not been reviewed for safety, effectiveness or quality.

Registro de fornecedores ao vivo · agrupado por dosagem

Cada fornecedor. Mais barato por mg primeiro; kits listados à parte.

RETATRUTIDE · preço por mg
2 ofertas · fornecedores sem alerta primeiro · Dados das ofertas atualizados pela última vez em outubro de 2026

Melhor preço por mg: Pepsup 20 mg a R$ 20,85/mg. Os kits saem mais baratos — R$ 11,10/mg, vendidos apenas em pacotes com vários frascos.

20 mg

1 oferta
01
PepsupVID-PEPSUP · €69,99 · tributos na entrega
20 mg
99%
Sem COA publicado (alegação do fabricante 99%+)
Em estoque
Envio dos Países Baixos · PostNL Tracked 2–5 dias úteis
R$ 20,85/mg
R$ 417

Kits · pacotes com vários frascos, preço por frasco

01
QSC PeptidesEscolhaVID-QSC-PEPT · Kit de 20 · US$ 430
10 mgkit de 20
99%
HPLC · MS · Janoshik
Em estoque
7–14 dias (internacional)
R$ 11,10/mg
R$ 111≈ R$ 2.220 por kit
Literatura representativa

Contexto de pesquisa. Trabalho recente revisado por pares.

2022 · Cell Metab.
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: from discovery to clinical proof of concept
2022 · Lancet
LY3437943, a novel triple GIP, GLP-1, and glucagon receptor agonist in people with type 2 diabetes: a phase 1b, multicentre, double-blind, placebo-controlled, randomised, multiple-ascending dose trial
citado por n = 72DOI ↗
2023 · N. Engl. J. Med.
Triple-hormone-receptor agonist retatrutide for obesity — a phase 2 trial
citado por n = 338DOI ↗
Perguntas frequentes

Dúvidas comuns.

Is retatrutide legal to buy?

It is not an approved medicine anywhere and the FDA states it cannot be used in compounding under federal law. Products sold research-use-only are for laboratory research, not human use; RUO labelling does not authorise personal use.

How is research-vial retatrutide different from a pharmacy product?

There is no approved pharmacy product to compare it with: retatrutide is investigational. Lilly states it is available only to its clinical-trial participants, so any vial sold commercially sits outside that controlled chain.

What should a CoA show for retatrutide?

HPLC purity, an LC-MS mass that matches the developer-published structure (vendor pages have been seen listing wrong CAS numbers and masses for this compound), a lot number, an independent third-party lab name and a test date.